Transdermal Patch Technology
Transdermal medical delivery and release systems have been on the market since 1982, after more than 20 years on extensive market research and development. Most major pharmaceutical companies now market Transdermal systems for dispensing a great variety of solid and liquid medical agents and solutions, including the now widely recognized anti-smoking Nicotine, clonodine, nitroglycerine, and estradiol, with many more to hit the market place.
Technology has evolved to a flexible system of multi-layered polymeric laminates and reservoir system which stores and releases active incredients under strict rate control, which can provide zero-order constant release for the life of the patch. The life can be programmed to range from one hour to several months. This technology eliminates any possibility of dosage dumping.
The Transdermal delivery and release system provides a highly efficient, safe, and each to use method for delivering active ingredients and other compounds to the body through intact skin, thereby offering many other advantages over the traditional dosage forms.
The Transdermal system consists of two integ technologies, the delivery and controlled release system and the chemical composition.
The Transdermal infusion of various ingredients into and through the dermis depends on osmosis through and between the squamous cell walls as they are presented in the epidermis and dermis of human tissue. Osmosis is the “flow of ions or molecules through a semi-permeable membrane (cell wall)”. The rate and quantity of osmosis of the ingredients are directly dependent upon the size of the individual molecule and the selection and quantity of the specific enhancer. The Transdermal patch, as formulated, consists of ingredients suspended and micro-dispersed in a unique matrix.
The Transdermal Patch is manufactured in compliance with all the rules and regulations promulgated by all regulatory agencies in the United States.